Supersaturated and non-digestible dispersions in the intestinal lumen: new mechanisms to reduce variability in the rate and extent of drug absorption

肠腔中的过饱和且不可消化的分散体：减少药物吸收速率和程度变异性的新机制

• 批准号: LP120100600
• 负责人: Prof Colin Pouton
• 金额: $ 23.64万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-03 至 2014-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP120100600
• 关键词: Supersaturated; non; digestible; dispersions; intestinal

This project will design new polymers to be included in capsule formulations to prevent the precipitation of drugs in the intestine after their oral administration. This new technology will reduce the incidence of side-effects and ensure that patients absorb the correct dose of drug regardless of whether they take the drug before or after food.

该项目将设计包含在胶囊制剂中的新聚合物，以防止口服给药后药物在肠道中沉淀。 这项新技术将减少副作用的发生率，并确保患者吸收正确剂量的药物，无论他们是在食物之前还是之后服用药物。