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Enabling novel circuit-based treatments for stroke: insights from cortical circuit monitoring and manipulation in mouse models.

Enabling novel circuit-based treatments for stroke: insights from cortical circuit monitoring and manipulation in mouse models.
实现基于回路的新型中风治疗：来自小鼠模型皮质回路监测和操作的见解。
批准号：
312474
负责人：
Murphy Timothy H
金额：
$211.37万
依托单位：
University of British Columbia
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2014
资助国家：
加拿大
项目状态：
已结题
起止时间：
2014-09-01 至 2021-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=312474&lang=en
关键词：
2-Photon Cortical Circuit Imaging Motor System Mouse Optogenetics Plasticity Sensorimotor Sensory System Stroke

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英文摘要
<html> <body> <p> <b>My overarching focus</b> is to understand how the cortex adapts after stroke, resulting in a remapping of function from damaged to surviving areas. By understanding the process at a circuit level, I hope to improve it using brain s
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3-dimensional representation of mouse movement and rapid interaction with cortical brain activity to describe and shape behavior to improve outcome from stroke: insights from real and synthetic data approaches.
  • 批准号：
    451251
  • 项目类别：
    Operating Grants
  • 资助金额：
    $83.04万
  • 财政年份：
    2021
  • 负责人：
    Murphy Timothy H
  • 依托单位：
    University of British Columbia
Probing the circuits responsible for stroke recovery with light-mediated circuit monitoring and manipulation in mouse models.
  • 批准号：
    210064
  • 项目类别：
    Operating Grants
  • 资助金额：
    $69.01万
  • 财政年份：
    2010
  • 负责人：
    Murphy Timothy H
  • 依托单位：
    University of British Columbia
Insight into sensorimotor cortex function and plasticity by monitoring and interrogating the brain-muscle interface using light.
  • 批准号：
    188795
  • 项目类别：
    Operating Grants
  • 资助金额：
    $73.15万
  • 财政年份：
    2009
  • 负责人：
    Murphy Timothy H
  • 依托单位：
    University of British Columbia
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