The role of symmetry and symmetry breaking in mitosis

对称性和对称性破缺在有丝分裂中的作用

• 批准号: 262246-2013
• 负责人: Vogel, Jackie
• 金额: $ 3.13万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=571255
• 关键词: role; symmetry; breaking; mitosis

Many aspects of cells are symmetric, and when they divide, two identical cells are formed. To create cells with different shapes and functions, a cell must contain information needed for each fate, and then partition asymmetrically it such that daughter cells will inherit different types of information and thus have different fates. We are investigating how the cellular machinery that physically divides the cell coordinates its activities in relation to asymmetrically distributed information.

细胞的许多方面是对称的，当它们分裂时，形成两个相同的细胞。为了创造具有不同形状和功能的细胞，一个细胞必须包含每种命运所需的信息，然后将其不对称地分割，使得子细胞将继承不同类型的信息，从而具有不同的命运。我们正在研究物理上划分细胞的细胞机制如何协调其与不对称分布信息有关的活动。