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The role of mRNA conformational dynamics in stimulating translational recoding

The role of mRNA conformational dynamics in stimulating translational recoding
mRNA构象动力学在刺激翻译重新编码中的作用
批准号:
320554
负责人:
Woodside Michael T
金额:
$53.99万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-03-01 至 2020-03-01

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中文摘要
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英文摘要
Proteins are assembled in the cell based on the genetic code, but this code can be altered by shifting the frame in which it is read. In viruses like HIV, SARS, and many others, such recoding is programmed into the genome using specific structures in the
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Using engineered heterodimers to probe prion-like propagation of misfolding in SOD1
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  • 财政年份:
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COVID-19 Variant Supplement - Targeting programmed ribosomal frameshifting as a therapeutic strategy against 2019-nCoV
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