Modulation-Encoded Micromachined Transducer Arrays for Ultrasound and Photoacoustic Imaging of Prostate and Colorectal Cancer

目前，医生使用超声成像等成像技术还不能很容易地看到前列腺癌。这意味着 许多生物检查和治疗策略都是相当盲目的。如果临床医生能把肿瘤和他们的 环境，并有一种方法来指导针吸活组织检查，并在节省的同时将治疗定向到需要的区域 健康的组织。这可能导致更安全的治疗策略，从而提高患有这种疾病的男性的生活质量。 我们的团队将利用微制造技术开发一种新型的3D超声和光学成像探头。这项技术 将允许目前不存在的高密度2D阵列。我们的团队将首先在实验室原型中完成开发， 然后实施经直肠/内窥镜外形因素，然后在狗模型和第一个人类飞行员身上测试这些设备 结直肠癌的研究以及前列腺治疗的影像指导。

Presently doctors cannot easily see prostate cancer using imaging techniques like ultrasound imaging. This means that many biospy and treatment strategies are quite blind. It would be so much better if clinicians could visualize tumors and their environment and have a way to guide needle biopsies and to direct treatment to the areas that are needed while sparing healthy tissue. This could lead to safer treatment strategies that could improve the quality of life for men with this disease. Our team will develop a novel 3D ultrasound and optical imaging probe using microfabrication technology. This technology will allow for high-density 2D arrays which do not currently exist. Our team will first complete development in a labprototype, then implement transrectal/endoscopic form-factors, then test the devices in dog models & first-in-human pilot studies for colorectal cancer as well as prostate therapy image-guidance.