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Translating genomic discoveries to cure ultrahypermutant mismatch repair deficient brain tumors

Translating genomic discoveries to cure ultrahypermutant mismatch repair deficient brain tumors
转化基因组发现来治疗超超突变错配修复缺陷脑肿瘤
批准号:
332326
负责人:
Tabori Uri
金额:
$0.0万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-06-01 至 2018-06-01

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中文摘要
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英文摘要
Malignant brain tumors are the most common cause of death form childhood cancer. Currently, our ability to cure these children is lacking. Many of these children will have inherited mutations which will be responsible for the brain tumor development. Usin
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会议论文
Uncovering the mechanism and impact of novel genetic and epigenetic promoter alterations on tissue-specific mismatch repair deficient cancers
Dissecting the origins and microenvironment of replication repair deficient hypermutant gliomas for novel immune based therapies
Biological and translational implications of replication repair deficiency and hypermutation in human cancer
Novel implications of THOR hypermethylation in telomere maintenance and gliomageneis.
国内基金
海外基金
联合基因组重测序和10× Genomics scRNA-Seq解析乌骨鸡胸肌黑色素转运的分子机制
  • 批准号:
    32072711
  • 项目类别:
    面上项目
  • 资助金额:
    58.0万元
  • 批准年份:
    2020
  • 负责人:
    郭松长
  • 依托单位:
Journal of Genetics and Genomics