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Prediction and Prevention of glioma recurrence by targeting telomere dependent self-renewal capacity of tumor initiating cells.

Prediction and Prevention of glioma recurrence by targeting telomere dependent self-renewal capacity of tumor initiating cells.
通过靶向肿瘤起始细胞的端粒依赖性自我更新能力来预测和预防神经胶质瘤复发。
批准号：
210910
负责人：
Tabori Uri
金额：
$55.18万
依托单位：
Hospital for Sick Children (Toronto)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2010
资助国家：
加拿大
项目状态：
已结题
起止时间：
2010-09-01 至 2015-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=210910&lang=en
关键词：
Expression Profile Glioma Snp Array Stem Cells Telomerase Telomeres Tumor Initiating Cells

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Pediatric neural tumors (neuroblastoma and brain tumors) are the main cause of death from childhood cancer. Death is almost always a result of their ability to relapse after maximal therapy with chemotherapy and radiation. New approaches are crucial for t
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Uncovering the mechanism and impact of novel genetic and epigenetic promoter alterations on tissue-specific mismatch repair deficient cancers
Dissecting the origins and microenvironment of replication repair deficient hypermutant gliomas for novel immune based therapies
Biological and translational implications of replication repair deficiency and hypermutation in human cancer
Translating genomic discoveries to cure ultrahypermutant mismatch repair deficient brain tumors
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双模式编码的慢病毒载体转染C6 Glioma Cells的影像学研究
  • 批准号：
    81271563
  • 项目类别：
    面上项目
  • 资助金额：
    60.0万元
  • 批准年份：
    2012
  • 负责人：
    陈正光
  • 依托单位：
    北京中医药大学