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Clinical and biological implications of monoallelic gene expression in pediatric malignant brain tumors.

Clinical and biological implications of monoallelic gene expression in pediatric malignant brain tumors.
小儿恶性脑肿瘤中单等位基因表达的临床和生物学意义。
批准号:
252418
负责人:
Tabori Uri
金额:
$41.78万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-03-01 至 2016-03-01

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中文摘要
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英文摘要
Malignant brain tumors are the leading cause of death in childhood cancer. There is an urgent need for new therapies to improve survival for these children. In the human genome, each gene has two copies, one from the mother and one from the father. In no
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Uncovering the mechanism and impact of novel genetic and epigenetic promoter alterations on tissue-specific mismatch repair deficient cancers
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Biological and translational implications of replication repair deficiency and hypermutation in human cancer
Translating genomic discoveries to cure ultrahypermutant mismatch repair deficient brain tumors
国内基金
海外基金
全外显子组测序(Whole-Exome Sequencing,WES)检测NSCLC中难治性OCT4+循环肿瘤细胞的基因突变
  • 批准号:
    81773273
  • 项目类别:
    面上项目
  • 资助金额:
    50.0万元
  • 批准年份:
    2017
  • 负责人:
    李榕
  • 依托单位: