Minimally-invasive, wireless, multimodal micro-optrodes for brain sensing

用于大脑传感的微创、无线、多模式微光极

• 批准号: 478458-2015
• 负责人: Messaddeq, Younès
• 金额: $ 9.11万
• 依托单位: Université Laval
• 依托单位国家: 加拿大
• 项目类别: Collaborative Health Research Projects
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=579524
• 关键词: Minimally; invasive; wireless; multimodal; micro

The proposed 3-year research project relates to the rapid convergence of Fiber optics, Wireless technology, and Neurological sciences to the study of brain activity. The project aims to combine the complementary expertise of physics, neurobiology, and electrical engineering of three leading research labs to develop a novel minimally-invasive, wireless, multimodal brain microprobe technology that will maximize the amount of brain activity, neurochemistry, cell signaling and ionic fluctuations acquired, with high temporal resolution, from freely behaving animals while minimizing significantly the size of the implant. The project involves experienced researchers in natural and health sciences, and a Canadian technology user organization. The project will accelerate ground breaking research towards new treatments for brain diseases like Alzheimers and Parkinsons disease, epilepsy, depression, obsessive-compulsive disorders and, chronic pain,driven mainly by age-related neurological disorders in an ageing population, by decreasing the cost and time of preclinical studies

拟议的为期 3 年的研究项目涉及光纤、无线技术和 神经科学研究大脑活动。该项目旨在结合物理学的互补专业知识， 三个领先研究实验室的神经生物学和电气工程共同开发一种新型微创、无线、 多模式脑微探针技术将最大限度地提高大脑活动、神经化学、细胞信号传导和 从自由行为的动物中获得高时间分辨率的离子波动，同时显着减小尺寸 植入物的。该项目涉及自然科学和健康科学领域经验丰富的研究人员以及加拿大技术 用户组织。 该项目将加速针对阿尔茨海默病等脑部疾病新疗法的突破性研究 帕金森病、癫痫、抑郁症、强迫症和慢性疼痛，主要由年龄相关引起 通过减少临床前研究的成本和时间来治疗老龄化人口中的神经系统疾病