Development of surface plasmon resonance biosensor based on immobilization of proteins on gold nanoparticles.

基于金纳米颗粒上蛋白质固定化的表面等离子共振生物传感器的开发。

• 批准号: 478698-2015
• 负责人: Guillemette, Guy
• 金额: $ 1.81万
• 依托单位: University of Waterloo
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=579734
• 关键词: Development; surface; plasmon; resonance; biosensor

Nicoya is interested in developing methods for the immobilization of peptides and proteins on sensors composed of gold nanoparticles. The immobilized biomolecular probes will be used for the optimization of sensor performance and the investigation of peptide-protein, protein-protein and protein ligand interactions. The results of this investigation will increase the types of life science applications that can be performed by the biosensor platform developed by Nicoya. Successful completion of this project will put Canada in a strong position in developing this useful biosensor platform.

Nicoya对开发将肽和蛋白质固定在由金纳米颗粒组成的传感器上的方法感兴趣。固定化的生物分子探针将用于优化传感器性能和研究肽-蛋白质，蛋白质-蛋白质和蛋白质配体相互作用。这项研究的结果将增加Nicoya开发的生物传感器平台可以执行的生命科学应用的类型。该项目的成功完成将使加拿大在开发这一有用的生物传感器平台方面处于有利地位。