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Synthetic biology for the genetic transformation of microalgae for the production of valuable plant metabolites

用于微藻遗传转化以生产有价值的植物代谢物的合成生物学

基本信息

批准号：
486086-2015
负责人：
DesgagnéPenix, Isabel
金额：
$ 1.82万
依托单位：
Université du Québec à Trois-Rivières
依托单位国家：
加拿大
项目类别：
Engage Grants Program
财政年份：
2015
资助国家：
加拿大
起止时间：
2015-01-01 至 2016-12-31
项目状态：
已结题

来源：
https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=585389
关键词：
Synthetic biology genetic transformation microalgae

项目摘要

SabrTech is a company specialized in algal biomass production. Creators of the RiverBox, the first modular, scalable, and rapidly deployable biofilm platform, SabrTech enables on-site production of algae for a wide variety of sectors (aquaculture, nutraceutical, cosmetic and biofuel). To date, many fuels, pharmaceuticals and cosmetic products are extracted from plants. These valuable plant natural products (PNPs) are often produced in low quantities in plants and extraction methods can be long and expensive. Thus, there is much interest in synthetic biology for developing microbial platforms to produce specific PNPs. Microalgae are well-known systems for plant biology and genetic engineering and are interesting and suitable hosts for the reconstitution of complex plant pathways. SabrTech wishes to translate synthetic biology research into industrial processes. This synthetic biology project aims to develop a transformation protocol to create microalgae platforms for the production of valuable PNPs. These ventures are motivated by consumer demand for products that are environmentally friendly, less expensive, and possess properties similar or superior with those generated by PNPs.

SabrTech是一家专门从事藻类生物质生产的公司。第一个模块化的RiverBox的创造者， SabrTech是一个可扩展且可快速部署的生物膜平台，能够在广泛的范围内现场生产藻类各种部门（水产养殖、营养保健品、化妆品和生物燃料）。迄今为止，许多燃料、药品和化妆品是从植物中提取的。这些有价值的植物天然产物（PNP）通常是由在植物中含量低，提取方法可能耗时长且昂贵。因此，人们对以下方面很感兴趣：合成生物学用于开发微生物平台以产生特定的PNP。微藻是众所周知的系统的植物生物学和基因工程，是有趣的和合适的宿主，复杂的植物路径。SabrTech希望将合成生物学研究转化为工业过程。这合成生物学项目旨在开发一种转化方案，为生物技术领域的生物技术创造微藻平台。生产有价值的PNPs。这些企业的动机是消费者对产品的需求，环境友好，价格较低，并具有与通过以下方式产生的那些类似或上级的性质： PNPs。