Using Near Infrared Spectroscopy to measure tissue localized tissue oxygenation as a measure of exercise stress during a cycling ergometer time trial.

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Metrics of fatigue like heart rate, oxygen consumption and frequency of breathing can be challenging to interpret or measure in the field. During exercise muscle oxygen saturation will decrease, while at rest it will increase. Muscle oxygenation can be measured using a near infrared spectroscopy device (NIRS). Pathonix's NIRS device is a mobile noninvasive optical method to assess muscle oxygen and hemoglobin. The rate at which oxygen returns to muscle during rest is the resaturation rate. We propose to investigate resaturation rate as a novel measure of fatigue in an exercising limb. This research will explore the relationships between novel NIRS muscle oxygenation and hemodynamics and current indicators of fatigue, to find a reliable noninvasive measure of fatigue during exercise. Subjects will first be measured for their maximal oxygen consumption (VO2max) via a graded exercise test. During the second visit, subjects will perform a time-to-exhaustion test at a constant intensity. Throughout both exercise tasks, heart rate, ventilation, oxygen consumption, and muscle oxygenation will be recorded. The individuals at Pathonix have advanced expertise in the clinical application of NIRS, however, at present, the utility of NIRS in the exercising athlete is limited. Dr. Koehle and his team at UBC are experts in exercise physiology and have the capability to explore the utility of this new technology for athletic performance. This research intends to compare a NIRS device to current indicators of fatigue and outline how novel measures of muscle oxygen and hemoglobin could be used by athletes as an index of fatigue. Cyclists are particularly interested in using technology to monitor and improve their performance. Canada's presence in cycling has been increasing every year. Canadian innovators have developed technologies that are being used by the top teams around the world. The proper development of this technology will solidify our position as a country at the forefront of sport science.