Development of new bedside optical imaging methods for non-invasive assessment of brain injury in neonates

点击翻译按钮获取中文摘要

The neonatal brain is particularly vulnerable to the biological consequences of prematurity, to birth asphyxia, congenital heart disease and other neonatal metabolic disorders. Brain injury and altered or delayed brain development in the neonatal period are associated with devastating neurodevelopmental consequences such as significant cognitive, motor, language and behavioural disabilities. Although mortality rates have decreased due to advances in clinical care, neurodevelopmental deficits have emerged as the most significant co-morbidity. Currently the lack of bedside quantitative tools to monitor and assess brain health is a critical barrier to improve outcome in at-risk neonates.