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Molecular basis of protein-ligand interactions.

Molecular basis of protein-ligand interactions.
蛋白质-配体相互作用的分子基础。
批准号:
RGPIN-2015-05057
负责人:
Bisaillon, Martin
金额:
$2.19万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-01-01 至 2016-12-31

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中文摘要
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英文摘要
The long-term objective of this research program is to understand the molecular mechanisms that dictate the interactions between proteins and their ligands. We are especially interested in proteins that interact with RNA, metal ions, and/or other proteins because there are still important gaps in our understanding of how proteins recognize these ligands. Viral proteins are especially well suited for these studies because a single protein frequently harbors many different enzymatic activities and can therefore interact with various ligands. In the current research program, we are focusing on two different proteins (NS4B and NS5A) from the Hepatitis C virus (HCV) and use them as powerful models to understand how proteins interact with ligands.
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Viral modulation of cellular RNA alternative splicing
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Molecular basis of protein-ligand interactions.
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Molecular basis of protein-ligand interactions.
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    RGPIN-2016-03916
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    Discovery Grants Program - Individual
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Molecular basis of protein-ligand interactions.
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    RGPIN-2016-03916
  • 项目类别:
    Discovery Grants Program - Individual
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