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Mendelian Randomization analysis of 5p15.33, telomere length and lung cancer risk: results from 14,324 cases and 10,783 controls in the Transdisciplinary Research in Cancer of the Lung (TRICL) group of the International Lung Cancer Consortium (ILCCO)

Mendelian Randomization analysis of 5p15.33, telomere length and lung cancer risk: results from 14,324 cases and 10,783 controls in the Transdisciplinary Research in Cancer of the Lung (TRICL) group of the International Lung Cancer Consortium (ILCCO)
5p15.33、端粒长度和肺癌风险的孟德尔随机分析：来自国际肺癌联盟 (ILCCO) 肺癌跨学科研究 (TRICL) 小组的 14,324 例病例和 10,783 例对照的结果
批准号：
345576
负责人：
Kachuri Mirlinda
金额：
$0.22万
依托单位：
Lunenfeld-Tanenbaum Research Institute (Toronto)
依托单位国家：
加拿大
项目类别：
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-01-01 至 2017-01-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=345576&lang=en
关键词：
Lung Cancer Mendelian Randomization Telomere Length Telomeres

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英文摘要
Telomeres are structures that cap the ends of chromosomes and play an important role in maintaining genome stability. In normal human cells, telomeres shorten with each round of cell division until they reach a critical length, which triggers cell death.
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Risk of non-Hodgkin lymphoma: associations with autoimmune status and telomere length
Fine mapping of chromosome 5p15.33 based on a targeted re-sequencing to identify novel lung cancer susceptibility loci
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