Base-Metal Complexes for Challenging Organometallic Transformations

具有挑战性的有机金属转化的贱金属配合物

• 批准号: 261742-2013
• 负责人: Johnson, Samuel
• 金额: $ 3.93万
• 依托单位: University of Windsor
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=594647
• 关键词: Base; Metal; Complexes; Challenging; Organometallic

This proposal describes approaches to render sustainable 1st-row transition metals, such as nickel and cobalt, as catalysts for applications such as the functionalization of C-H, C-F and C-O bonds. The short term goals of the projects involve identification of new ways to render these metals reactive towards traditionally inert bonds. Approaches to this include using ligand design or identifying new mechanisms for bond activation. The long term goal of each project is the commercial application of these catalytic technologies in fields such as pharmaceutical synthesis and biomass conversion.

本提案描述了使可持续的第一行过渡金属，如镍和钴，作为C-H， C-F和C-O键功能化等应用的催化剂的方法。该项目的短期目标包括确定新的方法，使这些金属对传统惰性键具有反应性。实现这一目标的方法包括使用配体设计或确定新的键激活机制。每个项目的长期目标是这些催化技术在药物合成和生物质转化等领域的商业应用。