Optical nanoscopy of cytoskeletal and synaptic remodeling in neurons

神经元细胞骨架和突触重塑的光学纳米显微镜

• 批准号: 357931
• 负责人: De Koninck Paul
• 金额: $ 57.12万
• 依托单位: Centre de recherche Universit Laval-Robert-Giffard (QC)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-10-01 至 2021-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=357931&lang=en
• 关键词: Biophotonics; Cellular And Molecular Neuroscience; Cytoskeleton; Fluorescence Lifetime Imaging; Fret; Glutamatergic Synapses; Single Molecule Imaging; Sted Nanoscopy; Super Resolution Microscopy; Synaptic Plasticity

Solving brain disorders requires knowledge of the molecular components, their architecture and spatial dynamics and their signaling interactions inside subcellular compartments. The scale of molecular components (e.g. nanometers) inside cells has however

解决大脑疾病需要了解分子成分及其结构 以及空间动力学及其在亚细胞室内的信号相互作用。这 然而，细胞内分子成分的尺度（例如纳米）