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Genetic Modifiers of CTG Trinucleotide Repeat Instability and Myotonic Dystrophy Pathogenesis.

Genetic Modifiers of CTG Trinucleotide Repeat Instability and Myotonic Dystrophy Pathogenesis.
CTG 三核苷酸重复不稳定性和强直性肌营养不良发病机制的遗传修饰。
批准号：
181715
负责人：
Pearson Christopher E
金额：
$34.74万
依托单位：
Hospital for Sick Children (Toronto)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2009
资助国家：
加拿大
项目状态：
已结题
起止时间：
2009-03-01 至 2012-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=181715&lang=en
关键词：
Dna Mutation Dna Replication/Dna Repair Genetic Instability Genome Stability Myotonic Dystrophy Repeat Instability

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中文摘要
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英文摘要
About 40 human diseases, including myotonic dystrophy, are inherited in a manner that the symptoms become worse down generations as well as worsening as the individual ages. These diseases are caused by DNA mutations in repeated DNA sequences. If one cons
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