Atomic Force Microscopy System for Biomedical, Materials, and Environmental Research

用于生物医学、材料和环境研究的原子力显微镜系统

• 批准号: RTI-2017-00308
• 负责人: Kim, Keekyoung
• 金额: $ 10.67万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=616629
• 关键词: Atomic; Force; Microscopy; System; Biomedical

Atomic force microscopy system (AFM) is one of the leading-edge scientific research tools for imaging, measuring, and manipulating samples at the nanoscale level. Specimen information is acquired by scanning its surface with a piezoelectrically driven mechanical probe. The requested AFM will be the only one on the Okanagan campus and, as such, it will be made available to all researchers on the campus. In this proposal, we highlight some of the multidisciplinary research performed by a diverse group of faculty that will benefit from this equipment. The researchers collaborating for this piece of equipment are from the fields of biomedical engineering, electrical engineering, environmental engineering, mechanical engineering, materials engineering, and biophysics. Therefore, the new AFM system will support current and future research activities of at least seven research programs from UBC’s Okanagan campus. The AFM system is an essential tool on any University campus and especially in the Okanagan campus where we have a strong contingency of materials and bio/nanomaterials researchers. Since there is no AFM system on the Okanagan campus nor in any of the local colleges or research facilities nearby, the travel to other institutions to make measurements has imposed a significant cost of travel and research delay for the respective research programs. More specifically, the discovery grants and strategic projects led by the applicants are urgently dependent on the use of an AFM system on our campus. From a long term perspective, we have several collaboration opportunities with the emerging local industries on the characterization of new materials that can be pursued using the AFM. Further delays will possibly result in losing some of our potential collaborations and significant damage to research programs. The proposed AFM system will be located in the CFI funded Integrated Bio-Micro/Nanotechnology Laboratory in the Engineering Building. We expect that the instrument will initially be used for about 20 hours per week but grow to close to or exceeding 140 hrs per month by users across the campus as the campus learns of the capabilities of the AFM. Therefore, there will be serious impacts to the research programs of many faculties. This equipment will support interdisciplinary research for approximately 20 graduate and undergraduate students. All students who will be working with the AFM will be thoroughly trained in how the AFM works, how to operate the AFM and how to interpret the data from the AFM. This includes the theory behind the tests, instrument calibration, sample preparation, experimental design, and data analysis. The use of the AFM will enhance their training in microscopy and surface characterization techniques immensely and truly allow the expansion of their research skills.

原子力显微镜系统（AFM）是一种先进的科学研究工具，用于在纳米尺度上对样品进行成像、测量和操作。通过用压电驱动的机械探针扫描其表面来获取试样信息。所要求的AFM将是Okanagan校园中唯一的AFM，因此，它将提供给校园中的所有研究人员。在本提案中，我们重点介绍了由不同教师群体进行的一些多学科研究，这些研究将受益于该设备。这台设备的研究人员来自生物医学工程，电气工程，环境工程，机械工程，材料工程和生物物理学领域。因此，新的AFM系统将支持UBC Okanagan校区至少七个研究项目的当前和未来研究活动。AFM系统是任何大学校园的重要工具，特别是在Okanagan校园，我们有很强的材料和生物/纳米材料研究人员的偶然性。由于在Okanagan校园内没有AFM系统，附近的任何当地学院或研究设施也没有，因此前往其他机构进行测量的旅行给各自的研究项目带来了巨大的旅行成本和研究延迟。更具体地说，由申请人领导的发现补助金和战略项目迫切依赖于在我们校园使用AFM系统。从长远的角度来看，我们有几个合作的机会与新兴的本地产业的表征新材料，可以追求使用原子力显微镜。进一步的拖延可能会导致我们失去一些潜在的合作，并对研究计划造成重大损害。拟议的AFM系统将位于工程大楼内的CFI资助的综合生物微/纳米技术实验室。我们预计，该仪器最初将用于每周约20小时，但增长到接近或超过140小时，每月由用户在整个校园的校园学习的AFM的能力。因此，许多院系的研究计划将受到严重影响。该设备将支持约20名研究生和本科生的跨学科研究。所有将与AFM一起工作的学生都将接受AFM如何工作，如何操作AFM以及如何解释AFM数据的全面培训。这包括测试背后的理论，仪器校准，样品制备，实验设计和数据分析。AFM的使用将极大地提高他们在显微镜和表面表征技术方面的培训，并真正扩大他们的研究技能。