Wireless X-Ray dosimeter for blood sterilization

用于血液灭菌的无线 X 射线剂量计

• 批准号: 474468-2014
• 负责人: Roy, Langis
• 金额: $ 4.01万
• 依托单位: Carleton University
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=618675
• 关键词: Wireless; Ray; dosimeter; blood; sterilization

The purpose of this grant is to enable research and development of a low power wireless, battery-less, system-on-chip, gamma/X-ray radiation dosimeter in a commercial CMOS technology, specifically intended for blood bag irradiation. The application of a commercially available CMOS process in the radiation dose monitoring of blood bags during irradiation has not been previously explored. Recently, much attention has been focused on irradiating blood bags prior to transfusion to avoid transmitting potential diseases from donors to patients and also to avoid receiver's potential resistance to the blood. The irradiation of blood bags is done via gamma- or X-ray radiation sources. A gamma radiation machine consists of a radiation secure shielding which contains the radioactive source element Cesium 137 with a half life of 30.2 years. Within the machine, 3 or 4 blood bags can be placed at a time for irradiation for a period of around 3 to 5 minutes. The X-ray based blood irradiation machine consists of an X-ray tube and other mechanical and electronics devices and can also irradiate 3 to 5 blood bags at the same time. According to the government and health monitoring bodies, a cumulative absorbed radiation dose of between 30 to 50 Gray has to be given to blood bags to consider them safe for transfusion. This mandate obligates the blood bag irradiation manufacturers such as Best Theratronics and Best Medical Canada to monitor the performance of the machines to ensure proper operation. The most important way to verify the correct dose to the blood bags is via the use of indicators placed on each blood bag. The current indicator sold by the company on blood bags utilizes color change on a paper-like material which turns from white to a shade of blue and the intensity changes based on the amount of radiation. This method of observing total dose relies on operator's judgement. The research team at Carleton University proposes to develop a novel wireless battery-less RFID tag solution that monitors and through wireless communication reports the cumulative radiation dose live to a receiver which allows the operator to decide whether the bags have been irradiated satisfactorily or not.

该补助金的目的是使低功耗无线，无电池，片上系统，伽马/X射线辐射剂量计的商业CMOS技术的研究和开发，专门用于血袋辐照。在辐照过程中，市售CMOS工艺在血袋辐射剂量监测中的应用先前尚未探索。近年来，人们越来越关注在输血前对血袋进行辐照，以避免将潜在的疾病从献血者传播给患者，并避免受血者对血液的潜在抵抗力。血袋的辐照是通过伽马射线或X射线辐射源进行的。伽马辐射机由辐射安全屏蔽组成，其中含有半衰期为30.2年的放射性源元素铯137。在机器内，一次可以放置3或4个血袋，用于照射约3至5分钟。X射线血液照射机由X射线管和其他机械、电子设备组成，还可以同时照射3至5个血袋。根据政府和卫生监测机构的说法，血袋必须接受30至50戈瑞的累积吸收辐射剂量，才能安全输血。该命令要求血袋辐照制造商（如Best Theratronics和Best Medical Canada）监测机器的性能，以确保正常运行。验证血袋正确剂量的最重要方法是使用放置在每个血袋上的指示器。该公司目前销售的血袋指示剂利用纸状材料的颜色变化，从白色变成蓝色，强度根据辐射量变化。这种观察总剂量的方法依赖于操作者的判断。卡尔顿大学的研究小组提出开发一种新型的无线无电池RFID标签解决方案，该解决方案监测并通过无线通信向接收器报告累积辐射剂量，从而使操作员能够决定行李是否已被满意地辐照。