Immunogenetic Interactions: Assessing the Capacity of Northern Species to Adapt to Infectious Disease

气候变化正在迅速改变疾病动态，病原体在以前不适宜居住/无法进入的环境中定居，几种新出现的疾病证明了这一点。我的研究项目感兴趣的是物种对疾病做出反应的适应潜力，总体目标是预测和减轻对生物多样性的威胁。目前的建议通过对与免疫反应相关的遗传变异进行全面扫描，来调查物种适应疾病的能力。具体地说，我打算回答以下问题：

Disease dynamics are rapidly being altered by climatic changes, with pathogens colonizing previously inhospitable/inaccessible environments as evidenced by several emerging diseases. My research program is interested in the adaptive potential of species to respond to disease with the overarching objective of predicting and mitigating threats to biodiversity. The current proposal investigates the capacity of species to adapt to disease by performing comprehensive scans of genetic variation associated with an immune response. Specifically, I aim to answer the following questions: