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Molecular mechanisms of muscle contraction

Molecular mechanisms of muscle contraction
肌肉收缩的分子机制
批准号:
RGPIN-2016-05317
负责人:
Rassier, Dilson
金额:
$5.25万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31

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中文摘要
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英文摘要
Muscle contraction is driven by the molecular motor myosin II while attached to actin filaments. Myosin molecules transform chemical energy extracted from adenosine tri-phosphate (ATP) into mechanical work. After an initial attachment between myosin and actin, ATP is hydrolyzed, and phosphate (Pi) and subsequently ADP are released from myosin. The molecule undergoes a conformational change - the power stroke - producing force and sliding the actin filament. The molecular mechanisms behind the conversion of chemical energy released from ATP into the myosin power stroke, and its amplification into muscle contraction is not well understood.
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Molecular mechanisms of myosin II-actin interactions
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Molecular mechanisms of muscle contraction
  • 批准号:
    RGPIN-2016-05317
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $5.25万
  • 财政年份:
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  • 负责人:
    Rassier, Dilson
  • 依托单位:
Molecular mechanisms of muscle contraction
  • 批准号:
    RGPIN-2016-05317
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $5.25万
  • 财政年份:
    2020
  • 负责人:
    Rassier, Dilson
  • 依托单位:
Molecular mechanisms of muscle contraction
  • 批准号:
    RGPIN-2016-05317
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $5.25万
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  • 负责人:
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