The Influence of Parental Experience On Brain Development, Behaviour, and Neuroplasticity

父母经历对大脑发育、行为和神经可塑性的影响

• 批准号: RGPIN-2016-05266
• 负责人: Gibb, Robbin
• 金额: $ 2.55万
• 依托单位: University of Lethbridge
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=631449
• 关键词: Influence; Parental; Experience; Brain; Development

One of the fundamental questions in behavioural neuroscience relates to how the brain develops to produce our complex motor, social, and cognitive abilities in adulthood. It is now clear that brain development does not follow a blueprint but rather the nascent brain is sculpted by preconception, prenatal, and postnatal experiences to produce a brain that can do marvelous things. But not all brains are the same and there is remarkable variability ranging from brilliance to less than optimal outcomes.Having demonstrated that both positive and negative experiences at different times can influence brain and behavioral development, I propose to systematically examine the effects of such experiences at several developmental time points including preconception (both sires and dams), gestational (dams), perinatal, and adolescence.

行为神经科学的基本问题之一涉及大脑如何发育以产生成年后复杂的运动、社交和认知能力。现在很清楚，大脑的发育并不遵循蓝图，而是新生的大脑是通过孕前、产前和产后经历塑造的，从而产生了可以做奇妙事情的大脑。但并非所有的大脑都是相同的，并且存在显着的差异，从聪明到不太理想的结果。在证明不同时期的积极和消极经历都会影响大脑和行为发展之后，我建议系统地研究这些经历在几个发育时间点的影响，包括受孕前（父亲和母亲）、妊娠期（母亲）、围产期和青春期。