Evolution and development of skeletal patterning

骨骼图案的进化和发展

• 批准号: RGPIN-2016-06724
• 负责人: Larsson, Hans
• 金额: $ 3.21万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=632134
• 关键词: Evolution; development; skeletal; patterning

The research program will examine the developmental and evolutionary biology of the vertebrate skeleton across large scale evolutionary transitions. Specifically, it will explore the interplay between developmental and evolutionary integration and variation in the skeleton across the fish to tetrapod and dinosaur to bird transitions using quantitative methods of shape description and gene expression. The two transitions are chosen because of their rich fossil record and wealth of developmental biology of relevant extant species. A set of complimentary projects are designed to bridge a broad interdisciplinary program that researches a spectrum from genetic evolution, to developmental mechanics, to biological imaging and quantitative phenomics, to evolutionary patterns, rates, and variation.

该研究计划将研究脊椎动物骨骼在大规模进化过渡中的发育和进化生物学。具体而言，它将使用定量的形状描述和基因表达的定量方法探索跨鱼与四足动物和恐龙的骨骼之间的相互作用，以及骨骼的变化与鸟类的变化。之所以选择这两个过渡，是因为它们具有丰富的化石记录和相关现有物种的大量发育生物学。一组免费项目旨在桥接一个广泛的跨学科计划，该计划研究了从遗传进化到发育力学，生物成像和定量现象学，再到进化模式，速率和变异的频谱。