Evolution and development of skeletal patterning

骨骼图案的进化和发展

• 批准号: RGPIN-2016-06724
• 负责人: Larsson, Hans
• 金额: $ 3.21万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=632134
• 关键词: Evolution; development; skeletal; patterning

The research program will examine the developmental and evolutionary biology of the vertebrate skeleton across large scale evolutionary transitions. Specifically, it will explore the interplay between developmental and evolutionary integration and variation in the skeleton across the fish to tetrapod and dinosaur to bird transitions using quantitative methods of shape description and gene expression. The two transitions are chosen because of their rich fossil record and wealth of developmental biology of relevant extant species. A set of complimentary projects are designed to bridge a broad interdisciplinary program that researches a spectrum from genetic evolution, to developmental mechanics, to biological imaging and quantitative phenomics, to evolutionary patterns, rates, and variation.

该研究项目将研究脊椎动物骨骼在大规模进化过渡中的发育和进化生物学。具体来说，它将探讨发展和进化的整合和变化之间的相互作用，在整个鱼类的骨骼四足动物和恐龙鸟类的过渡使用定量方法的形状描述和基因表达。选择这两个过渡是因为它们有丰富的化石记录和丰富的相关现存物种的发育生物学。一套免费的项目旨在弥合广泛的跨学科计划，研究从遗传进化，发展机制，生物成像和定量表型组学，进化模式，速率和变异的频谱。