Design and development of radio frequency components for a new portable benchtop NMR spectrometer

新型便携式台式核磁共振波谱仪射频组件的设计和开发

• 批准号: 506178-2016
• 负责人: Schurko, Robert
• 金额: $ 1.82万
• 依托单位: University of Windsor
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=610134
• 关键词: Design; development; radio; frequency; components

PROTO Manufacturing (PROTO, Oldcastle, ON) has been designing, manufacturing, and selling X-ray diffraction (XRD) equipment since 1967, and has extensive expertise in fabrication of scientific benchtop instrumentation. Recently, PROTO has become interested in expanding their lineup of benchtop instrumentation to include a portable, low-field, nuclear magnetic resonance (NMR) spectrometer, since there is a clear need for such instrumentation in academic and industrial environments. At present, commercially available benchtop NMR spectrometers (BNS) are limited in terms of their portability, restricted modularity, and range of applications (e.g., basic applications in teaching laboratories). PROTO wishes to collaborate with Prof. Robert W. Schurko at the University of Windsor, who has expertise in the design and application of NMR probes and advanced NMR acquisition methods. The collaboration will focus on the development and design of a probe, amplifiers, and experimental techniques needed for PROTO's BNS. The proposed BNS will be made competitive with current instruments by: (i) designing a BNS that is more portable, modular, and inexpensive; and (ii) developing experiments and applications that are widely applicable in not only teaching environments (the current focus of most BNS systems), but also in industrial laboratories (e.g., pharmaceuticals, oil/energy), on-site applications (e.g., environmental sampling), and hospitals (e.g., high-throughput sampling of biological fluids and tissues). The development of this BNS will allow PROTO to expand into the NMR sector and to better compete with international companies, leading to net socioeconomic benefits for Canada.

PROTO Manufacturing（PROTO，Oldcastle，ON）自1967年以来一直在设计，制造和销售X射线衍射（XRD）设备，并在科学台式仪器的制造方面拥有丰富的专业知识。最近，PROTO对扩大其台式仪器阵容感兴趣，包括便携式低场核磁共振（NMR）光谱仪，因为学术和工业环境中明显需要这种仪器。目前，可商购的台式NMR光谱仪（BNS）在其便携性、受限的模块性和应用范围（例如，教学实验室的基本应用）。PROTO希望与Robert W. Schurko博士，他在核磁共振探针的设计和应用以及先进的核磁共振采集方法方面具有专业知识。此次合作将集中在PROTO BNS所需的探头、放大器和实验技术的开发和设计上。拟议的BNS将通过以下方式与现有仪器竞争：（i）设计一种更加便携、模块化和廉价的BNS;以及（ii）开发不仅广泛适用于教学环境（大多数BNS系统目前的重点），而且广泛适用于工业实验室（例如，制药、石油/能源），现场应用（例如，环境取样），和医院（例如，生物流体和组织的高通量取样）。该BNS的开发将使PROTO能够扩展到NMR行业，并更好地与国际公司竞争，从而为加拿大带来净社会经济效益。