Supramolecular Dynamics in Solution and in Gels

溶液和凝胶中的超分子动力学

• 批准号: RGPIN-2017-04458
• 负责人: Bohne, Cornelia
• 金额: $ 5.39万
• 依托单位: University of Victoria
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=632555
• 关键词: Supramolecular; Dynamics; Solution; Gels

Supramolecular chemistry occupies the space between individual molecules and macroscopic systems in terms of complexity and functionality. Two key features of supramolecular systems are: 1) the reversible assembly of a supermolecule from molecular building blocks and 2) the co-existence of related species that compete with one another. These characteristics are those exhibited in very complex macroscopic living systems. My research aims to understand the dynamic nature of supramolecular systems and will provide the concepts necessary for rational control of these systems from the kinetic point of view. Such kinetic control, which is currently lacking, will open new ways to design functional materials, where the dynamics of the components are essential for function. The research proposed is at the forefront of fundamental studies and does not directly address any particular function, but the outcomes have implications for any supramolecular system where binding and release of building blocks is integral to function, such as membrane transport, drug delivery, catalysis, or stimuli-responsive materials. The proposed research is allied with “systems chemistry”, in which interactions of molecular building blocks produce new properties that the individual components cannot achieve on their own.

超分子化学在复杂性和功能性方面占据了单个分子和宏观系统之间的空间。超分子系统的两个关键特征是：1）从分子构建块可逆组装超分子和2）相互竞争的相关物种的共存。这些特征是在非常复杂的宏观生命系统中表现出来的。我的研究旨在了解超分子系统的动态性质，并将提供从动力学角度合理控制这些系统所需的概念。目前缺乏的这种动力学控制将为设计功能材料开辟新的途径，其中组件的动力学对于功能至关重要。这项研究处于基础研究的最前沿，并不直接涉及任何特定的功能，但其结果对任何超分子系统都有影响，其中构建模块的结合和释放是功能不可或缺的，例如膜转运，药物递送，催化或刺激响应材料。拟议的研究与“系统化学”有关，其中分子构建块的相互作用产生了单个组件无法自行实现的新特性。