Frontiers in Olefin Metathesis & Metathesis-Derived Nanomaterials

烯烃复分解的前沿

• 批准号: RGPIN-2017-06950
• 负责人: Fogg, Deryn
• 金额: $ 5.39万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=632728
• 关键词: Frontiers; Olefin; Metathesis; Derived; Nanomaterials

Olefin metathesis is the most powerful and versatile method now known for building new carbon-carbon bonds, and hence the frameworks of new molecules. Its applications range from the assembly of new drugs to utilization of renewable resources, as cited in the Nobel Prize for metathesis in 2005. Uptake in pharmaceutical and specialty-chemicals manufacturing, anticipated for decades, is a very recent reality. Metathesis is being used to access new, potent viral inhibitors, and to transform renewable plant oils into specialty chemicals.

烯烃复分解是目前已知的用于构建新的碳-碳键并因此构建新分子框架的最强大和最通用的方法。它的应用范围从组装新药到利用可再生资源，如2005年诺贝尔复分解奖所述。制药和特种化学品制造业的吸收，预计几十年，是最近的现实。复分解被用于获得新的，有效的病毒抑制剂，并将可再生植物油转化为特种化学品。