Chemical Synthesis and Applications of Nucleic Acid Analogues

核酸类似物的化学合成及应用

• 批准号: RGPIN-2016-05126
• 负责人: Damha, Masad
• 金额: $ 6.63万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=632854
• 关键词: Chemical; Synthesis; Applications; Nucleic; Acid

Nucleic acids are the fundamental molecules of life, carrying the genetic blueprints for all living things on Earth. Refined through billions of years of evolution, they achieve an ideal balance between complexity and elegance, a perfect marriage of form and function. As such, synthetic DNA and RNA oligonucleotides and their analogues are incredibly useful tools for molecular biology, functional genomics, and biochemistry research.

核酸是生命的基本分子，携带着地球上所有生物的遗传蓝图。经过数十亿年的进化，它们在复杂性和优雅性之间达到了理想的平衡，是形式和功能的完美结合。因此，合成的DNA和RNA寡核苷酸及其类似物是分子生物学，功能基因组学和生物化学研究的非常有用的工具。