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Contribution to neuroinflammation of immunometabolic reprogramming of resident microglia and infiltrating macrophages

Contribution to neuroinflammation of immunometabolic reprogramming of resident microglia and infiltrating macrophages
常驻小胶质细胞和浸润巨噬细胞的免疫代谢重编程对神经炎症的贡献
批准号：
376093
负责人：
Auger Jean-Philippe
金额：
$10.93万
依托单位：
Friedrich-Alexander University (Germany)
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2017
资助国家：
加拿大
项目状态：
已结题
起止时间：
2017-11-01 至 2020-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=376093&lang=en
关键词：
Experimental Autoimmune Encephalomyelitis Flow Cytometry Immunometabolism In Vivo Mouse Model Macrophages Metabolic Reprogramming Microglia Monocyte-Derived Macrophages Neuroinflammation Transgenic Mice

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Macrophages are tissue-resident cells that fulfill homeostatic functions, notably in the central nervous system. Following assault, they become activated and secrete mediators that lead to a local inflammation (neuroinflammation). Moreover, large numbers
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