Biochemical profiling and activity of the botanical extract CELEXT07
植物提取物 CELEXT07 的生化分析和活性
基本信息
- 批准号:521107-2017
- 负责人:
- 金额:$ 0.91万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Engage Plus Grants Program
- 财政年份:2017
- 资助国家:加拿大
- 起止时间:2017-01-01 至 2018-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The mission and vision of Mondias Naturals Inc (MNI) is to commercialize evidence-based botanicalantimicrobial products for the residential, organic and commercial agricultural markets. Mondias has identifiedseveral herb extracts including CELEX07 that have antimicrobial activity. The previous NSERC-ENGAGEproposal (Application number 506182-16) was related to the needs of the industrial partner MNI to evaluate theuse of plant extracts as biopesticides against economically important diseases of plant crops. The main focus ofMNI was to obtain information on the minimum inhibitory concentration (MIC) of their botanical aqueousextracts (BE) prepared from plant roots of Chelidonium majus, (referred to as CELEX 07) against bacterial andfungal pathogens of tomato, tobacco and lettuce young plants, and compare CELEXT07 efficacy to existingbotanical extracts products found on the market (Yarrow and Thyme flower extracts). The results confirmedthat CELEXT07 applied as soil drench at the MIC 1% concentration showed growth stimulatory effect(increased plant height and weight) of tobacco and lettuce young plants compared to non-treated plants orplants treated with a combined dose of yarrow and CELEXT07. Armed with this knowledge, MNI is keen toaddress the following questions and objectives through NSERC Engage Plus: (1) What are the activemetabolites of CELEXT07 prepared from root and leaf organs (2) Identify the signatory metabolite groupresponsible for growth stimulation of plants (e.g., phytohormones) and increased resistance (e.g., phenolics)against selective pathogens. (3) Carry out large-scale greenhouse experiments toevaluate the efficacy ofCELEXT07 extracts from root vs. leaf for disease suppression of Botrytis cinerea and Xanthomonascampestris, the causal agents of grey mould and bacterial leaf spots on lettuce, respectively.The execution of the above objectives will provide Mondias Naturals Inc. an independent assessment andscientific evidence on the active metabolite in the botanical extract CELEX07 as well as the biotechnologicalpotential to develop a monotherapy-type line of formulations targeted for specific agricultural markets.
Mondias Naturals Inc (MNI)的使命和愿景是为住宅,有机和商业农业市场商业化基于证据的植物抗菌产品。Mondias已经确定了几种具有抗菌活性的草药提取物,包括CELEX07。先前的nserc - engage提案(申请号506182-16)与工业合作伙伴MNI的需求有关,以评估植物提取物作为生物农药的使用,以防止植物作物的重要经济疾病。mni的主要重点是获得从Chelidonium majus植物根中提取的植物水提取物(celex07)对番茄、烟草和生菜幼苗的细菌和真菌病原体的最低抑制浓度(MIC)信息,并将CELEXT07与市场上现有的植物提取物产品(蓍草和百里香花提取物)的功效进行比较。结果证实,与未处理或蓍草和CELEXT07联合剂量处理的幼苗相比,在最小浓度为1%时,CELEXT07作为土壤水剂对烟草和生菜幼苗的生长有促进作用(增加株高和株重)。有了这些知识,MNI热衷于通过NSERC Engage Plus解决以下问题和目标:(1)从根和叶器官制备的CELEXT07的活性代谢物是什么?(2)确定负责刺激植物生长的标志代谢物组(例如植物激素)和增加对选择性病原体的抗性(例如酚类物质)。(3)开展大规模温室试验,评价celext07根提取物与叶提取物对生菜灰霉病病原灰霉病菌灰霉病菌灰霉病菌灰霉病菌和细菌性叶斑病菌黄病菌(xanthomascampestris)的抑制效果。上述目标的实现将为Mondias Naturals Inc.提供关于植物提取物CELEX07中活性代谢物的独立评估和科学证据,以及开发针对特定农业市场的单一疗法型配方的生物技术潜力。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Jabaji, Suha其他文献
Comparative transcriptome analysis reveals the biocontrol mechanism of Bacillus velezensis E68 against Fusarium graminearum DAOMC 180378, the causal agent of Fusarium head blight.
比较转录组分析揭示了Velezensis E68与法利群谷物Daomc 180378的生物防治机制,这是镰刀菌Head Blight的因果剂。
- DOI:
10.1371/journal.pone.0277983 - 发表时间:
2023 - 期刊:
- 影响因子:3.7
- 作者:
Liang, Nathan;Charron, Jean-Benoit;Jabaji, Suha - 通讯作者:
Jabaji, Suha
Chemotaxonomy of fungi in the Rhizoctonia solani species complex performing GC/MS metabolite profiling
- DOI:
10.1007/s11306-011-0340-1 - 发表时间:
2013-03-01 - 期刊:
- 影响因子:3.6
- 作者:
Aliferis, Konstantinos A.;Cubeta, Marc A.;Jabaji, Suha - 通讯作者:
Jabaji, Suha
Comparison of cyanobacterial microcystin synthetase (mcy) E gene transcript levels, mcy E gene copies, and biomass as indicators of microcystin risk under laboratory and field conditions.
- DOI:
10.1002/mbo3.173 - 发表时间:
2014-08 - 期刊:
- 影响因子:3.4
- 作者:
Ngwa, Felexce F.;Madramootoo, Chandra A.;Jabaji, Suha - 通讯作者:
Jabaji, Suha
Maple Bark Biochar Affects Rhizoctonia solani Metabolism and Increases Damping-Off Severity
- DOI:
10.1094/phyto-08-14-0231-r - 发表时间:
2015-10-01 - 期刊:
- 影响因子:3.2
- 作者:
Copley, Tanya R.;Aliferis, Konstantinos A.;Jabaji, Suha - 通讯作者:
Jabaji, Suha
Gene Expression and Isoflavone Concentrations in Soybean Sprouts Treated with Chitosan
- DOI:
10.2135/cropsci2007.09.0536 - 发表时间:
2009-01-01 - 期刊:
- 影响因子:2.3
- 作者:
Chen, Huilan;Seguin, Philippe;Jabaji, Suha - 通讯作者:
Jabaji, Suha
Jabaji, Suha的其他文献
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{{ truncateString('Jabaji, Suha', 18)}}的其他基金
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维生素 B6 在植物-微生物相互作用中作为抗氧化剂的作用
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$ 0.91万 - 项目类别:
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The next generation agriculture:spinach-associated microbes as the new pesticide against plant and food borne pathogens in the agrifood sector
下一代农业:菠菜相关微生物作为农业食品领域针对植物和食源性病原体的新型杀虫剂
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561224-2020 - 财政年份:2021
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$ 0.91万 - 项目类别:
Alliance Grants
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RGPIN-2016-04805 - 财政年份:2021
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$ 0.91万 - 项目类别:
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Plant Resistance: Antioxidant Perspective View of Plant-Fungal Pathogen Interactions
植物抗性:植物-真菌病原体相互作用的抗氧化视角
- 批准号:
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$ 0.91万 - 项目类别:
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Enhancement of the biological control capabilities of Bacillus velezensis strain OB9 using nanotechnology approaches
利用纳米技术方法增强贝莱斯芽孢杆菌OB9菌株的生物防治能力
- 批准号:
557192-2020 - 财政年份:2020
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$ 0.91万 - 项目类别:
Idea to Innovation
Characterisation and antimicrobial activity of essential oils of medicinal plants
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- 批准号:
542648-2019 - 财政年份:2019
- 资助金额:
$ 0.91万 - 项目类别:
Engage Grants Program
Plant Resistance: Antioxidant Perspective View of Plant-Fungal Pathogen Interactions
植物抗性:植物-真菌病原体相互作用的抗氧化视角
- 批准号:
RGPIN-2016-04805 - 财政年份:2019
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$ 0.91万 - 项目类别:
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$ 0.91万 - 项目类别:
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$ 0.91万 - 项目类别:
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Plant Resistance: Antioxidant Perspective View of Plant-Fungal Pathogen Interactions
植物抗性:植物-真菌病原体相互作用的抗氧化视角
- 批准号:
RGPIN-2016-04805 - 财政年份:2017
- 资助金额:
$ 0.91万 - 项目类别:
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