Disinfectant effects on antimicrobial resistance

消毒剂对抗菌药物耐药性的影响

• 批准号: 536004-2018
• 负责人: Andres, Sara
• 金额: $ 1.82万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=643960
• 关键词: Disinfectant; effects; antimicrobial; resistance

Preventing the transmission of infectious diseases is aided by the use of disinfectants on various surfaces, including the surfaces of medical equipment and in hospitals. However, like the misuse and overuse of antibiotics, mounting evidence suggests that the use of disinfectants may lead to resistant bacteria. Virox Technologies Inc., which produces an environmentally-friendly disinfectant with multi-patented Accelerated Hydrogen Peroxide (AHP) technology, in collaboration with the Andres lab at McMaster University, will investigate whether disinfectants are promoting bacterial resistance, and if so, how bacterial resistance arises. Understanding the mechanism by which bacteria tolerate and survive disinfection will allow for the development of better disinfectant formulations that will mitigate the generation of bacterial resistance, providing a stronger line of defense in the prevention of infectious diseases.

通过在各种表面，包括医疗设备表面和医院内使用消毒剂，有助于防止传染病的传播。然而，就像滥用和过度使用抗生素一样，越来越多的证据表明，使用消毒剂可能会导致细菌产生抗药性。Virox Technologies Inc.与麦克马斯特大学安德烈斯实验室合作，生产一种具有多项专利的加速过氧化氢(AHP)技术的环境友好消毒剂，该公司将调查消毒剂是否会增加细菌耐药性，如果是，细菌耐药性是如何产生的。了解细菌耐受和在消毒中存活的机制将有助于开发更好的消毒剂配方，从而减轻细菌耐药性的产生，在预防传染病方面提供更强大的防线。