Structural and functional investigations of the human transcription machinery by ion mobility-mass spectrometry

通过离子淌度-质谱法对人类转录机制进行结构和功能研究

• 批准号: DP110100496
• 负责人: Prof Tara Pukala
• 金额: $ 23.91万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2017-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP110100496
• 关键词: Structural; functional; investigations; human; transcription

This project will apply emerging mass spectrometric technologies to gain previously inaccessible insight into human transcription factor proteins. This will reveal new avenues for intervention in human disease states related to aberrant gene expression, while developing innovative methods for the study of complex protein assemblies.

该项目将应用新兴的质谱技术，以获得以前无法深入了解人类转录因子蛋白质。这将揭示干预与异常基因表达相关的人类疾病状态的新途径，同时开发研究复杂蛋白质组装的创新方法。