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Reducing Homeostatic Synaptic Plasticity: A New Antiepileptogenic Approach to Cure Focal Epilepsy

Reducing Homeostatic Synaptic Plasticity: A New Antiepileptogenic Approach to Cure Focal Epilepsy
降低稳态突触可塑性：一种治疗局灶性癫痫的新抗癫痫方法
批准号：
400740
负责人：
Avoli Massimo
金额：
$54.62万
依托单位：
Montreal Neurological Institute-Hospital
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2019
资助国家：
加拿大
项目状态：
已结题
起止时间：
2019-03-01 至 2024-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=400740&lang=en
关键词：
Eeg Recordings In Vivo Epileptogenesis Field/Whole Cell In Vitro Recordings Hippocampus Homeostatic Synaptic Plasticity Mesial Temporal Lobe Epilepsy Mice Optogenetic Stimulation Pilocarpine Principal Cells

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中文摘要
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英文摘要
Our goal is to control the biological processes that occur in the brain after an initial insult (e.g., status epilepticus, SE) and lead to focal epileptic disorders such as mesial temporal lobe epilepsy (MTLE), the most common type of adult refractory epi
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