Discovery and Creation of Metal Carbonyl (MC) Supramolecular Chemistry

金属羰基（MC）超分子化学的发现和创造

• 批准号: RGPIN-2016-04497
• 负责人: Wang, Xiaosong
• 金额: $ 1.82万
• 依托单位: University of Waterloo
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=680598
• 关键词: Discovery; Creation; Metal; Carbonyl; MC

Based on Dr Wang's invention of migration insertion polymerization (MIP) and recent discoveries of metal carbonyl (MC) self-assembled vesicles, MC supramolecular chemistry is proposed. The originality and novelty of the proposed work will lead to new directions of research for several fields, including supramolecular chemistry, organometallic polymer and colloids. With sufficient support, Dr Wang will be an international leader in these fields.******Dr Wang discovered that hydrophobic, non-surface active CpPPh3Fe(CO)CO(CH2)5CH3 (FpC6), as an MC building block, can self-assemble in water into uniform vesicles with high membrane integration. The colloids are stabilized via the balance of water-carbonyl interaction (WCI), hydrophobic hydration (HH) and hydrophobic interaction (HI). This aqueous behavior of MCs bears a resemblance to many natural systems, e.g. proteins. MC supramolecular chemistry will therefore offer an experimental system to verify the arbitrary theories for WCI, HH and HI established mainly based on complicated biological systems and computation chemistry. ***FpC6 is also able to assemble in solid state into the first example of well-characterized supramolecular duplex chains via intermolecular pi-pi interaction and hydrogen bonding with CO as acceptor. This discovery is achieved via reverse crystal engineering. By varying the chemical structure of MCs, assembling conditions and additives, unusual opportunities arise to learn the synergy of multiple interactions that is essential for designed synthesis. The duplex chains, rarely observed, are potentially useful materials with combined properties of macromolecules and locally ordered MC groups, providing new concepts for industrial R covered with MCs. This unique feature will be explored for potential applications as nanoreactors and scavengers for contaminants in water. ***This research will: 1) create an experimental system bridging natural assembling systems and supramolecular chemistry; 2) create new concepts for novel materials; 3) advance a number of scientific frontiers, including organometallic polymers, supramolecular chemistry and aqueous colloids; 4) provide a cutting-edge training platform. Canadian science and industry will therefore benefit from the expected world-firsts in knowledge and HQPs behind them.******

基于王博士的迁移插入聚合（MIP）的发明和最近发现的金属羰基（MC）自组装囊泡，MC超分子化学被提出。这项工作的独创性和新颖性将为包括超分子化学、有机金属聚合物和胶体在内的几个领域带来新的研究方向。有了足够的支持，王博士将成为这些领域的国际领导者。******王博士发现疏水、非表面活性的CpPPh3Fe(CO)CO(CH2)5CH3 （FpC6）作为MC的组成单元，可以在水中自组装成均匀的囊泡，具有高的膜集成度。胶体通过水-羰基相互作用（WCI）、疏水水合作用（HH）和疏水相互作用（HI）的平衡得到稳定。MCs的这种水性行为与许多自然系统（如蛋白质）相似。因此，MC超分子化学将为验证主要基于复杂生物系统和计算化学建立的WCI、HH和HI的任意理论提供一个实验体系。***FpC6还能够通过分子间pi-pi相互作用和以CO为受体的氢键，在固态下组装成第一个表征良好的超分子双链。这一发现是通过逆向晶体工程实现的。通过改变MCs的化学结构、组装条件和添加剂，我们有机会了解多种相互作用的协同作用，这对设计合成至关重要。双链是一种罕见的具有大分子和局部有序MC基团组合性质的潜在有用材料，为MC覆盖的工业R提供了新的概念。这种独特的特性将被探索作为纳米反应器和水中污染物清除剂的潜在应用。***本研究将：1)建立一个连接自然组装系统和超分子化学的实验系统；2)为新材料创造新概念；3)推进有机金属聚合物、超分子化学、水性胶体等科学前沿；4)提供最前沿的培训平台。因此，加拿大的科学和工业将受益于预期的世界第一的知识和背后的hqp ******