Exploring the properties of Gadusol for the purpose of using it to develop new UV filters for use in cosmeticproduct

探索 Gadusol 的特性，以利用其开发用于化妆品的新型紫外线过滤剂

• 批准号: 549183-2019
• 负责人: Rogers, Ben
• 金额: $ 1.82万
• 依托单位: Seneca College of Applied Arts and Technology
• 依托单位国家: 加拿大
• 项目类别: Applied Research and Development Grants - Level 1
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=680704
• 关键词: Exploring; properties; Gadusol; purpose; using

Acanthus Research is developing new UV filters for use in cosmetic products. These nature-inspiredUV-protective compounds may eventually replace currently used chemicals that pose serious safety concerns for human health and the environment. This project involves investigation of the toxicity of several derivatives of gadusol and their effectiveness in protecting against harmful UV radiation and free-radical mediated skin photo-ageing. Acanthus does not currently have the expertise or facilities to do this research in-house.Collaborating with Professor Maryna Premyslova at Seneca's School of Biological Science Applied Chemistry will provide scientific data, which will enable Acanthus to make key decisions about their strategy for product formulation, development, and commercialization. The prevalence of skin cancer and the threat of photo-aging is driving growth in the global market for sun protection products, which is predicted to reach over $11.1billion this year. It is generally accepted that growth in the coming years will be driven by the development of more effective sun care and anti-aging active ingredients. Toxicity and efficacy data, together with the results of in-house stability studies and formulation development will put Acanthus in excellent position to seekadditional grants or partners for commercialization. This will lead to job creation and economic growth.

Acanthus Research正在开发用于化妆品的新型紫外线过滤剂。这些自然启发的紫外线防护化合物最终可能取代目前使用的对人类健康和环境造成严重安全问题的化学品。该项目涉及调查几种gadusol衍生物的毒性及其在防止有害紫外线辐射和自由基介导的皮肤光老化方面的有效性。Acanthus目前没有专业知识或设施在内部进行这项研究。与Seneca生物科学应用化学学院的Maryna Premyslova教授合作将提供科学数据，这将使Acanthus能够就其产品配方，开发和商业化战略做出关键决策。皮肤癌的流行和光老化的威胁正在推动全球防晒产品市场的增长，预计今年将达到111亿美元以上。人们普遍认为，未来几年的增长将受到更有效的防晒和抗衰老活性成分的开发的推动。毒性和功效数据，以及内部稳定性研究和配方开发的结果，将使Acanthus处于寻求额外赠款或商业化合作伙伴的绝佳位置。这将导致创造就业机会和经济增长。