Miniaturized Biomedical Devices

小型化生物医学设备

• 批准号: 1000230944-2015
• 负责人: Soleymani, Leyla
• 金额: $ 8.74万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=693225
• 关键词: Miniaturized; Biomedical; Devices

Point-of-care diagnostic systems are envisioned to significantly improve the quality of healthcare by bringing complex disease diagnostic and screening tests, currently performed at centralized laboratories, to patients locations. However, only a few systems have been commercialized for diagnosis, prognosis, and treatment selection of cancers, infectious diseases, hereditary disease, etc. The proposed research is expected to transform the way these systems are manufactured by employing ink-based fabrication methods to create structurally-tuned solid-phase electronics functionalized with bio-receptors. This will allow multiple biomedical devices for processing clinical samples and detecting genetic markers to be miniaturized and created on a single scalable and inexpensive system.

床旁诊断系统被设想为通过将目前在集中实验室进行的复杂疾病诊断和筛查测试带到患者位置来显著提高医疗保健质量。然而，只有少数系统已商业化的诊断，预后和治疗选择癌症，传染病，遗传性疾病等拟议的研究预计将改变这些系统的制造方式，采用基于墨水的制造方法，以创建结构调谐的固相电子功能化与生物受体。这将允许用于处理临床样本和检测遗传标记的多个生物医学设备被小型化并在单个可扩展且廉价的系统上创建。