课题基金 / 基金详情

Integrative and Translational Biomedical Engineering

Integrative and Translational Biomedical Engineering
综合与转化生物医学工程
批准号:
CRC-2018-00085
负责人:
Juncker, David
金额:
$14.57万
依托单位:
依托单位国家:
加拿大
项目类别:
Canada Research Chairs
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-01-01 至 2020-12-31

项目摘要

项目成果

Juncker, David的其他基金

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相关文献

中文摘要
翻译
多组学分析正在增强精准医学的能力,并正在引领一种整合组学和生理数据的预防和预后医学的新范式。细胞外囊泡和(罕见的)循环细胞携带其起源的分子指纹,并提供上下文丰富的信息,但不被考虑。在这里,容克博士提出了一个三模态分析平台,利用他实验室开发的技术捕获蛋白质、细胞外囊泡和罕见的循环细胞。三模态分析将在乳腺癌和转移性肝癌患者中进行优化和验证。三模态分析将加强多组分析,导致更准确的预后,早期诊断,最终预防医学。
英文摘要
Multiomic analysis is empowering precision medicine and is leading to a new paradigm of preventative and prognostic medicine integrating omic and physiological data. Extracellular vesicles and (rare) circulating cells carry the molecular fingerprints of their origin, and provide context-rich information, but are not considered. Here, Dr. Juncker proposes a trimodal analysis platform capturing protein, extracellular vesicles, and rare circulating cells using technologies developed in his lab. The trimodal analysis will be optimized and validated with breast and metastatic liver cancer patients. Trimodal analysis will enhance multiomic analysis, lead to more accurate prognosis, earlier diagnosis, and eventually preventative medicine.
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Integrative and Translational Biomedical Engineering
  • 批准号:
    CRC-2018-00085
  • 项目类别:
    Canada Research Chairs
  • 资助金额:
    $14.57万
  • 财政年份:
    2022
  • 负责人:
    Juncker, David
  • 依托单位:
Microfluidic Chain Reaction: Exploration, Expansion, and Application
  • 批准号:
    RGPIN-2022-05171
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $5.61万
  • 财政年份:
    2022
  • 负责人:
    Juncker, David
  • 依托单位:
Integrative And Translational Biomedical Engineering
  • 批准号:
    CRC-2018-00085
  • 项目类别:
    Canada Research Chairs
  • 资助金额:
    $14.57万
  • 财政年份:
    2021
  • 负责人:
    Juncker, David
  • 依托单位:
Elements and systems for ultrasensitive protein analysis
  • 批准号:
    RGPIN-2016-06723
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $7.87万
  • 财政年份:
    2021
  • 负责人:
    Juncker, David
  • 依托单位:
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