Development of a Novel Therapy to Prevent Breast Cancer Metastasis: Modulation of TAFI, a Master Regulator of Extracellular Proteolysis

开发预防乳腺癌转移的新疗法：调节 TAFI（细胞外蛋白水解的主调节因子）

• 批准号: 435642
• 负责人: Boffa Michael B
• 金额: $ 52.67万
• 依托单位: University of Western Ontario
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-10-01 至 2025-10-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=435642&lang=en
• 关键词: Breast Cancer; Extracellular Proteolysis; Metastasis; Mouse Models; Thrombin-Activatable Fibrinolysis Inhibitor (Tafi); Thrombomodulin

Over 90% of cancer deaths are caused by metastasis, the spreading of cancer from the primary tumor site to other parts of the body. Dr. Boffa and his team have discovered a new way to potentially prevent this process. Metastasis depends in part on a group

超过90%的癌症死亡是由转移引起的，转移是指癌症从原发肿瘤部位扩散到身体其他部位。博法博士和他的团队已经发现了一种可能阻止这一过程的新方法。转移在一定程度上取决于一个群体