New Directions in Supramolecular and Coordination Chemistry

超分子与配位化学的新方向

• 批准号: RGPIN-2017-04899
• 负责人: MacLachlan, Mark
• 金额: $ 9.03万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=710882
• 关键词: New; Directions; Supramolecular; Coordination; Chemistry

Supramolecular chemistry, the subject of the 1987 Nobel Prize in Chemistry (and the basis of the 2016 Nobel Prize in Chemistry), is a flourishing field that exploits weak intermolecular interactions to create complex structures from simpler building blocks. This is Nature's way: building complexity from the bottom up. Using supramolecular approaches, chemists are building molecular knots, transistors, and sensors, to name only a few of the exciting developments. In our research program, we use supramolecular templating to construct complex materials. For example, using cellulose nanocrystals (CNCs) as templates, we have been able to make photonic hydrogels that respond to stimuli, chiral porous silica that can be used to separate enantiomers, and photonic plastics that can be imprinted with photonic patterns. During our most recent NSERC Discovery Grant period, we have made several other significant contributions in the field of supramolecular chemistry and materials, including development of campestarenes, a class of molecules with 5-fold symmetry; discovery of hexagonal nanotubular assemblies from triptycene derivatives using OH---Br bonding; and a detailed understanding of tautomerization in imines formed from triformylphloroglucinol. In this proposal, we build on our past accomplishments to investigate a new concept, using rigid, shape-persistent macrocycles as templates to construct polymetallic complexes and nanofibres. We will investigate the synthesis and characterization of rigid macrocycles and cleft-shaped molecules. These will be functionalized to form superligands that are designed to host polymetallic complexes. The coordination chemistry, aggregation, and molecular dynamics of the new organic molecules will be investigated. The long term goal is to use the macrocycles as templates for constructing metal and metal oxide nanowires that may become part of future computer technology. As well, we hope that the molecular complexes will serve as mimics for metalloenzymes, offering unique electronic, optical, magnetic, and catalytic properties that we can explore. This Discovery grant will train students at all levels: graduate, undergraduate, and post-doctorate. HQP involved in the proposed work will receive world-class training in a dynamic, multidisciplinary research environment that includes opportunities to interact with industry and take part in professional development workshops and opportunities. In addition to receiving hands-on training on extensive equipment available, trainees will work on challenging projects that stimulate their curiosity and acumen in science, best preparing them for their careers.

超分子化学是1987年诺贝尔化学奖的主题（也是2016年诺贝尔化学奖的基础），是一个蓬勃发展的领域，它利用弱分子间相互作用，从更简单的构建块中创造复杂的结构。这是大自然的方式：从下到上构建复杂性。使用超分子方法，化学家们正在制造分子结、晶体管和传感器，这只是令人兴奋的发展中的一小部分。