New Directions in Supramolecular and Coordination Chemistry

超分子与配位化学的新方向

• 批准号: RGPIN-2017-04899
• 负责人: MacLachlan, Mark
• 金额: $ 9.03万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=658313
• 关键词: New; Directions; Supramolecular; Coordination; Chemistry

Supramolecular chemistry, the subject of the 1987 Nobel Prize in Chemistry (and the basis of the 2016 Nobel Prize in Chemistry), is a flourishing field that exploits weak intermolecular interactions to create complex structures from simpler building blocks. This is Nature's way: building complexity from the bottom up. Using supramolecular approaches, chemists are building molecular knots, transistors, and sensors, to name only a few of the exciting developments.******In our research program, we use supramolecular templating to construct complex materials. For example, using cellulose nanocrystals (CNCs) as templates, we have been able to make photonic hydrogels that respond to stimuli, chiral porous silica that can be used to separate enantiomers, and photonic plastics that can be imprinted with photonic patterns. During our most recent NSERC Discovery Grant period, we have made several other significant contributions in the field of supramolecular chemistry and materials, including development of campestarenes, a class of molecules with 5-fold symmetry; discovery of hexagonal nanotubular assemblies from triptycene derivatives using OH---Br bonding; and a detailed understanding of tautomerization in imines formed from triformylphloroglucinol.******In this proposal, we build on our past accomplishments to investigate a new concept, using rigid, shape-persistent macrocycles as templates to construct polymetallic complexes and nanofibres. We will investigate the synthesis and characterization of rigid macrocycles and cleft-shaped molecules. These will be functionalized to form superligands that are designed to host polymetallic complexes. The coordination chemistry, aggregation, and molecular dynamics of the new organic molecules will be investigated. The long term goal is to use the macrocycles as templates for constructing metal and metal oxide nanowires that may become part of future computer technology. As well, we hope that the molecular complexes will serve as mimics for metalloenzymes, offering unique electronic, optical, magnetic, and catalytic properties that we can explore.******This Discovery grant will train students at all levels: graduate, undergraduate, and post-doctorate. HQP involved in the proposed work will receive world-class training in a dynamic, multidisciplinary research environment that includes opportunities to interact with industry and take part in professional development workshops and opportunities. In addition to receiving hands-on training on extensive equipment available, trainees will work on challenging projects that stimulate their curiosity and acumen in science, best preparing them for their careers.

超分子化学是1987年诺贝尔化学奖的主题（也是2016年诺贝尔化学奖的基础），是一个蓬勃发展的领域，利用弱分子间相互作用从简单的构建块中创建复杂的结构。这就是自然的方式：自下而上构建复杂性。 使用超分子方法，化学家正在构建分子结，晶体管和传感器，仅举几个令人兴奋的发展。在我们的研究计划中，我们使用超分子模板来构建复杂的材料。例如，使用纤维素纳米晶体（CNC）作为模板，我们已经能够制造对刺激有反应的光子水凝胶，可用于分离对映异构体的手性多孔二氧化硅，以及可压印光子图案的光子塑料。在我们最近的NSERC发现资助期间，我们在超分子化学和材料领域做出了其他几项重要贡献，包括campestarenes的开发，一类具有5重对称性的分子;发现使用OH-Br键合的三蝶烯衍生物的六边形纳米管组装;以及对由三甲酰间苯三酚形成的亚胺中的互变异构的详细理解。在这项提案中，我们建立在我们过去的成就，调查一个新的概念，使用刚性，形状持久的大环作为模板，以构建多金属络合物和纳米纤维。我们将研究刚性大环和裂缝形分子的合成和表征。这些将被官能化以形成超配体，所述超配体被设计成容纳多金属络合物。将研究新有机分子的配位化学、聚集和分子动力学。长期目标是使用大环作为模板来构建金属和金属氧化物纳米线，这些纳米线可能成为未来计算机技术的一部分。同样，我们希望分子复合物将作为金属酶的模拟物，提供我们可以探索的独特的电子，光学，磁性和催化特性。这个发现补助金将培养学生在各个层次：研究生，本科和博士后。参与拟议工作的HQP将在动态的多学科研究环境中接受世界一流的培训，其中包括与行业互动的机会，并参加专业发展研讨会和机会。除了接受有关广泛设备的实践培训外，学员还将从事具有挑战性的项目，激发他们对科学的好奇心和敏锐性，为他们的职业生涯做好最好的准备。