A Stress Activated Znf281 Signalling Pathway Can be Therapeutically Targeted to Prevent Chemotherapy-Induced Cardiotoxicity
应激激活的 Znf281 信号通路可作为治疗靶点预防化疗引起的心脏毒性
基本信息
- 批准号:451325
- 负责人:
- 金额:$ 69.66万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Operating Grants
- 财政年份:2021
- 资助国家:加拿大
- 起止时间:2021-09-01 至 2026-09-01
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
Early cancer diagnosis and better treatment options have significantly increased the survival of cancer patients. However, the most common and severe adverse problem for these patients continues to be the development of heart failure as a direct consequen
早期癌症诊断和更好的治疗选择显著提高了癌症患者的生存率。然而,这些患者最常见和最严重的不良问题仍然是直接导致心力衰竭的发展
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Sutendra Gopinath其他文献
Sutendra Gopinath的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Sutendra Gopinath', 18)}}的其他基金
Tumor-Secreted Nucleosides Can Promote RbFox1 Degradation and Signalling Pathways Relevant to Dedifferentiation in Cardiomyocytes; A Two-Hit Hypothesis with Implications for Cardiotoxicity
肿瘤分泌核苷可促进 RbFox1 降解以及与心肌细胞去分化相关的信号通路;
- 批准号:
467633 - 财政年份:2022
- 资助金额:
$ 69.66万 - 项目类别:
Operating Grants
Activation of Pyruvate Kinase M2 as a Novel Therapy for Chemotherapy-Induced Cardiotoxicity
激活丙酮酸激酶 M2 作为化疗引起的心脏毒性的新疗法
- 批准号:
355953 - 财政年份:2016
- 资助金额:
$ 69.66万 - 项目类别:
Operating Grants
相似海外基金
YTHDF3 as a critical regulator of cardiac function
YTHDF3 作为心脏功能的关键调节因子
- 批准号:
10676427 - 财政年份:2023
- 资助金额:
$ 69.66万 - 项目类别:
Elucidating the Maintenance Mechanism of Cardiac Function by a Novel Human lncRNA and Potential Application in the Development of Therapies for Heart Failure
新型人类lncRNA阐明心脏功能的维持机制及其在心力衰竭疗法开发中的潜在应用
- 批准号:
23K07511 - 财政年份:2023
- 资助金额:
$ 69.66万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Roles of Rad and other CaV1.2 neighboring proteins in regulating cardiac function in health and disease
Rad 和其他 CaV1.2 邻近蛋白在健康和疾病中调节心脏功能中的作用
- 批准号:
10628915 - 财政年份:2023
- 资助金额:
$ 69.66万 - 项目类别:
Mechanical Load Effects on Cardiac Function and Heart Diseases
机械负荷对心脏功能和心脏病的影响
- 批准号:
10573078 - 财政年份:2023
- 资助金额:
$ 69.66万 - 项目类别:
CAREER: How Does the Heart Contract? A Microstructure-Based Approach to Understand Cardiac Function and Dysfunction
职业:心脏如何收缩?
- 批准号:
2237391 - 财政年份:2023
- 资助金额:
$ 69.66万 - 项目类别:
Standard Grant
The relation of residual inflammation and impaired cardiac function in patients post myocarditis using PETMR system
使用PETMR系统研究心肌炎后患者残余炎症与心功能受损的关系
- 批准号:
22K07701 - 财政年份:2022
- 资助金额:
$ 69.66万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
AI-Enabled Assessment of Cardiac Function from Echocardiography
人工智能通过超声心动图评估心脏功能
- 批准号:
2740000 - 财政年份:2022
- 资助金额:
$ 69.66万 - 项目类别:
Studentship
Relating gene expression to protein regulation for increased cardiac function in zebrafish (Danio rerio) during cold acclimation
将基因表达与冷驯化期间斑马鱼(Danio rerio)心脏功能增强的蛋白质调节联系起来
- 批准号:
580823-2022 - 财政年份:2022
- 资助金额:
$ 69.66万 - 项目类别:
Alexander Graham Bell Canada Graduate Scholarships - Master's
The ECM as a coordinator of cardiac function, growth and morphogenesis during heart development
ECM 作为心脏发育过程中心脏功能、生长和形态发生的协调者
- 批准号:
BB/W004305/1 - 财政年份:2022
- 资助金额:
$ 69.66万 - 项目类别:
Research Grant
Glyoxalase-1 loaded nanoparticles for reducing methylglyoxal and promoting vascular repair and cardiac function after myocardial infarction
负载乙二醛酶-1的纳米颗粒可减少心肌梗死后的甲基乙二醛并促进血管修复和心脏功能
- 批准号:
462351 - 财政年份:2022
- 资助金额:
$ 69.66万 - 项目类别:
Operating Grants














{{item.name}}会员




