Translating Academic Discoveries in Radical-Trapping Antioxidant Chemistry to Commercial Technology Development

将自由基捕获抗氧化化学的学术发现转化为商业技术开发

• 批准号: 566299-2021
• 负责人: Pratt, Derek
• 金额: $ 11.17万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Alliance Grants
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=721048
• 关键词: Translating; Academic; Discoveries; Radical; Trapping

Hydrocarbon autoxidation is a spontaneous process that limits the longevity of living matter and the products made from the fossil fuels that derive therefrom. Antioxidants are added to essentially all hydrocarbon-based products to slow their degradation via autoxidation. A particularly important application of antioxidants is in engine lubricants. The high-temperatures and pressures to which lubricants are exposed during engine operation greatly facilitates their oxidative degradation. Ever increasing fuel economy standards and growing awareness that we must minimize fossil fuel consumption necessitates improvements in antioxidant technology, which has remained largely unchanged for 50 years. Exciting discoveries in the Pratt laboratory at the University of Ottawa have the potential to address this need. Translation of these discoveries to commercial products would be enabled by improved methods to assess efficacy in test formulations where interactions with other lubricant components could be rapidly identified and optimized. Likewise, means to monitor the fate of the antioxidants under operating conditions would provide insights on structural modifications that maximize antioxidant lifetime. This proposal aims to validate chemical tools that will enable the development of the next generation of antioxidants. The proposed partnership with Petro-Canada Lubricants (PCL) and Infineum International (Infineum) provides the ideal platform for translation. PCL is Canada's largest supplier of finished lubricants, which are prepared by blending the highly refined base oils they produce in Mississauga with mixtures of antioxidants and other additives. Infineum is one of the world's leading formulators, manufacturers and marketers of fuel and lubricant additives, and supply PCL with additive packages used in their heavy duty diesel engine oils, passenger car motor oils and automatic transmission fluids. Infineum has the know-how and resources to translate discoveries made in the Pratt laboratory to products that can be incorporated into the next generation of PCL products, providing not only economic benefits to Canada, but also contributing to reduced consumption of fossil fuel-derived products here and around the world.

碳氢化合物自氧化是一种自发过程，它限制了生命物质的寿命和由从中推导的化石燃料制成的产品。将抗氧化剂添加到所有基本上所有碳氢化合物的产品中，以通过自氧化降低其降解。抗氧化剂的一种特别重要的应用是发动机润滑剂。发动机操作期间暴露于润滑剂的高温和压力极大地促进了它们的氧化降解。燃油经济性标准的提高和越来越多的意识，我们必须最大程度地减少化石燃料消耗需要改善抗氧化技术，而抗氧化技术已经在很大程度上保持不变了50年。渥太华大学普拉特实验室的令人兴奋的发现有可能满足这一需求。这些发现将这些发现转换为商业产品将通过改进的方法来评估可以快速识别和优化其他润滑剂组件相互作用的测试配方中的功效。同样，在工作条件下监测抗氧化剂的命运的方法将提供有关最大化抗氧化剂寿命的结构修饰的见解。该建议旨在验证化学工具，以使下一代抗氧化剂的发展。拟议的与石油加拿大润滑剂（PCL）和Infineum International（Infineum）的合作伙伴关系为翻译提供了理想的平台。 PCL是加拿大最大的成品润滑剂供应商，它们是通过将他们在密西沙加（Mississauga）和抗氧化剂和其他添加剂混合物混合的高度精制基础油混合而成的。 Infineum是全球领先的配制剂，燃料和润滑剂添加剂的制造商和营销商之一，并为PCL提供了重型柴油机油，乘用车机油和自动变速箱液体中使用的添加剂包。 Infineum拥有专有技术和资源，可以将Pratt实验室中的发现转化为可以纳入下一代PCL产品的产品，这不仅为加拿大提供了经济利益，而且还有助于减少在这里和世界各地的化石燃料衍生产品的消费。