Development of novel azaphenoxazine and azaphenothiazine antioxidants for applications as additives to petroleum-derived products

开发新型氮杂吩恶嗪和氮杂吩噻嗪抗氧化剂，用作石油衍生产品的添加剂

• 批准号: 508790-2017
• 负责人: Pratt, Derek
• 金额: $ 4.55万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=662585
• 关键词: Development; novel; azaphenoxazine; azaphenothiazine; antioxidants

Hydrocarbons - raw or transformed into industrial chemicals or consumer products - are highly susceptible to oxidative deterioration, a process mediated by free radicals. As such, radical-trapping antioxidants comprise some of the more important chemical additives to virtually all petroleum-derived materials, from oils, fuels and rubber to plastics, cosmetics and consumer products. The vast majority of the additives used today were developed over half a century ago as unsuccessful efforts to develop novel chemical scaffolds with superior reactivity, but good stability, has lead to stagnation in the development of new technologies. Recent NSERC-funded research on the chemistry of radical-trapping antioxidants in the applicant's laboratories has lead to the conception of a new class of antioxidant compounds that have exciting commercial potential. Herein we propose to undertake a collaborative project with BASF Canada to help develop this technology into a product that could enhance the longevity of multiple BASF products produced in Canada, as well as Canadian petroleum-derived products which rely on BASF additives to ensure their longevity.

碳氢化合物--未加工或转化为工业化学品或消费品--极易发生氧化劣化，这是一个由自由基介导的过程。因此，捕捉自由基的抗氧化剂包含了几乎所有石油衍生材料的一些更重要的化学添加剂，从石油、燃料和橡胶到塑料、化妆品和消费品。今天使用的绝大多数添加剂是半个多世纪前开发的，因为开发具有优异反应活性但稳定性好的新型化学支架的努力失败，导致新技术的开发停滞不前。最近由NSERC资助的申请人实验室中关于捕捉自由基的抗氧化剂化学的研究导致了一种具有令人兴奋的商业潜力的新型抗氧化剂化合物的概念。在此，我们建议与巴斯夫加拿大公司开展一个合作项目，以帮助将这项技术开发成一种产品，该产品可以提高加拿大生产的多种巴斯夫产品的寿命，以及依赖巴斯夫添加剂确保其寿命的加拿大石油衍生产品。