Development of novel azaphenoxazine and azaphenothiazine antioxidants for applications as additives to petroleum-derived products

开发新型氮杂吩恶嗪和氮杂吩噻嗪抗氧化剂，用作石油衍生产品的添加剂

• 批准号: 508790-2017
• 负责人: Pratt, Derek
• 金额: $ 4.55万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=662585
• 关键词: Development; novel; azaphenoxazine; azaphenothiazine; antioxidants

Hydrocarbons - raw or transformed into industrial chemicals or consumer products - are highly susceptible to oxidative deterioration, a process mediated by free radicals. As such, radical-trapping antioxidants comprise some of the more important chemical additives to virtually all petroleum-derived materials, from oils, fuels and rubber to plastics, cosmetics and consumer products. The vast majority of the additives used today were developed over half a century ago as unsuccessful efforts to develop novel chemical scaffolds with superior reactivity, but good stability, has lead to stagnation in the development of new technologies. Recent NSERC-funded research on the chemistry of radical-trapping antioxidants in the applicant's laboratories has lead to the conception of a new class of antioxidant compounds that have exciting commercial potential. Herein we propose to undertake a collaborative project with BASF Canada to help develop this technology into a product that could enhance the longevity of multiple BASF products produced in Canada, as well as Canadian petroleum-derived products which rely on BASF additives to ensure their longevity.

碳氢化合物 - 原始或转化为工业化学品或消费产品 - 非常容易受到氧化恶化的影响，这是由自由基介导的过程。因此，自由基捕获抗氧化剂包括一些更重要的化学添加剂到几乎所有石油衍生的材料，从油，燃料和橡胶到塑料，化妆品和消费品。半个世纪前，当今使用的绝大多数添加剂是开发的，因为不成功地开发具有较高反应性的新型化学脚手架，但良好的稳定性导致了新技术的发展。 NSERC资助的最新研究对申请人实验室中自由基诱捕抗氧化剂化学的研究导致了具有令人兴奋的商业潜力的新型抗氧化剂化合物的概念。在此，我们建议与加拿大巴斯夫开展一个合作项目，以帮助将该技术开发到可以提高加拿大生产的多种巴斯夫产品的寿命以及加拿大石油衍生产品的产品，这些产品依赖于巴斯夫添加剂来确保其寿命。