Analysis of oxidative stress on off-target infection of activated T cells by oncolytic vesicular stomatitis virus

溶瘤性水泡性口炎病毒活化T细胞脱靶感染氧化应激分析

• 批准号: 467024
• 负责人: Vanderkamp Sierra
• 金额: $ 1.27万
• 依托单位: University of Guelph
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-12-01 至 2022-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=467024&lang=en
• 关键词: Cancer Immunotherapy; Immunology; Oncolytic Virotherapy; Virology

Oncolytic virotherapy is a form of cancer therapy that utilizes oncolytic viruses (OVs) to preferentially infect and kill tumour cells. We have previously demonstrated that some OVs in clinical trials likely lack efficacy due to the off-target infection o

溶瘤病毒疗法是一种利用溶瘤病毒（OVs）优先感染和杀死肿瘤细胞的癌症疗法。我们以前已经证明，临床试验中的一些OV可能由于靶外感染而缺乏疗效。