CD5 antigen-like as a regulator of neuroinflammation in a chronic stress-induced mouse model of Major Depressive Disorder

CD5 抗原样作为慢性应激诱导的重度抑郁症小鼠模型中神经炎症的调节剂

• 批准号: 476325
• 负责人: Uthayakumar Deeva
• 金额: $ 7.65万
• 依托单位: Sunnybrook Research Institute (Toronto, Ontario)
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-11-01 至 2025-11-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=476325&lang=en
• 关键词: Anti-Inflammatory Microglia; Crystallography; Depression And Mental Health; Flow Cytometry; Immunometabolism; Murine Behavioural Studies; Neuro-Immune Interactions; Sex Dimorphisms; Single-Cell Rna Sequencing

Major depressive disorder (MDD), commonly referred to as depression, is a mental disorder that is a leading cause of disability and suicide worldwide. Afflicting millions of Canadians, MDD is the most common outcome of chronic stress, with women twice as

重度抑郁症（MDD），通常被称为抑郁症，是一种精神障碍，是世界范围内导致残疾和自杀的主要原因。重度抑郁症折磨着数百万加拿大人，是慢性压力最常见的结果，女性是女性的两倍