Innovative biomedical microsystems driven by data and artificial intelligence

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This research program is at the interface of engineering, neuroscience, assistive technology and life sciences, and addresses the world's most important questions in the field of biomedical technologies, including human performance enhancement, drug discovery, brain diseases, and aging. In particular, the focus is on the creation of new approaches to improve human performance through new smart myoelectric prostheses, and to enhance experimental neuroscience research with novel high-precision tools. In conjunction with the Canada Research Chair in Smart Biomedical Microsystems, this research will be truly enabling and will propel Canada at the forefront of the international scientific scene. Three important research aims will be covered by this program: Aim 1) Create on-chip edge AI (artificial intelligence) strategies that will allow developing closed-loop brain therapies with nearly zero latency, Aim 2) Design ultra-high-density myoelectric controllers with embedded AI providing regressive control, and Aim 3) Design the world's smallest integrated sensors providing medical-grade vital signs measurement. It should be noted that an important focus of this program is on developing in-sensor intelligence drawing from machine learning techniques to avoid latency and enhance sensor precision in Aims 1 to 3. The long-term vision of the program is to foster the creation of new groundbreaking technology drawing from medical instrumentation, material science, AI and advanced microsystems manufacturing to increase biomedical systems intelligence and functionality while pushing their miniaturization to unprecedented levels. Another long-term objective is to continue developing an excellent and inclusive training environment for researchers at all levels in the field of intelligent biomedical technologies. The research proposed in this application is extremely original and innovative and is likely to have impact by leading to groundbreaking advances in preclinical research, assistive technology, and personalized medicine. This program will potentially lead to technologies or policies addressing urgent socio-economic needs to develop better therapeutics against mood disorders, improve the quality of life of people living with a disability and contribute to make personalized medicine becoming a reality. The students involved will participate to international conferences to present their work and building their network. They will learn and develop new advanced skills to address several key challenges in biomedical technology and AI towards the development of groundbreaking devices of added value. They will also develop unique expertise in multi-technology integration, and will gain practical experience in advanced manufacturing, which will be transferred to the Canadian industry when they will take positions, or when they will interact directly with end users during or after this research.