Bridging Across Scales and Disciplines: Simulation-based Design and Optimization of Tightly Coupled Thermal/Fluid Systems

跨尺度和学科的桥梁：紧耦合热/流体系统的基于仿真的设计和优化

• 批准号: RGPIN-2019-04798
• 负责人: Amon, Cristina
• 金额: $ 6.63万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=759619
• 关键词: Bridging; Across; Scales; Disciplines; Simulation

Modelling and simulation of coupled, multi-scale, multi-physics phenomena are crucial for the design and optimization of novel, complex engineered systems. For instance, cutting-edge developments in battery technologies, enabling the electric vehicle (EV) revolution, require consideration of thermal, electrical, and chemical phenomena and their impact at the component and system levels. Similarly, transformative tissue engineering and organ regeneration technologies seek to maximize yield by effecting precise control of cells' chemical, biological and mechanical environments at the micro- and macro-scale. In all these applications, thermal and fluid flow phenomena are key to system performance, yet simultaneous consideration of other physical domains (electrical, chemical, biological) is needed for accurate predictions of system performance. We will develop a methodology for multi-scale, multi-physics modeling, simulation and optimization for these and other applications, where performance is both enabled and constrained by tight, non-linear coupling between multiple physical phenomena across multiple length/time scales. In particular, we will focus on applications in (a) high-performance materials and structures for electronics (transistors) and energy storage (batteries), (b) thermo-electro-chemical management of intelligent batteries for EVs, and (c) tissue engineering technologies for organ regeneration. Powered by the proposed methodology, we will (i) increase our understanding of the physical processes underlying these applications at the nano-, meso- and macro-scales, through both simulations and experiments, (ii) optimize the performance of battery cells and tissue bioreactors and experimental protocols, and (iii) train the next generation of engineers that will support Canada's global technological leadership, leveraging our lab's unique position as a collaborative research hub for multiple engineering and biomedical disciplines. The outcomes of this project will allow designers to tailor system geometry, materials, structures and operating conditions across multiple length scales to revolutionize system performance. Leveraging this knowledge, engineers across the globe can unleash their potential and creativity to envision innovative designs and rapidly test them with state-of-the-art computer simulations instead of costly, time-consuming experiments.

耦合，多尺度的多物理现象的建模和模拟对于新颖，复杂的工程系统的设计和优化至关重要。例如，电池技术的尖端发展，实现电动汽车革命（EV）革命，需要考虑热，电和化学现象及其在组件和系统水平上的影响。同样，转化组织工程和器官再生技术试图通过在微观和宏观尺度上对细胞的化学，生物学和机械环境进行精确控制，以最大程度地提高产量。在所有这些应用中，热和流体流现象是系统性能的关键，但需要同时考虑其他物理领域（电气，化学，生物学）来准确地预测系统性能。我们将开发一种用于对这些和其他应用程序的多尺度，多物理建模，仿真和优化的方法，在这种方法中，性能既可以通过多个长度/时间尺度上的多个物理现象之间的紧密，非线性耦合来启用和约束。特别是，我们将重点关注（a）电子设备（晶体管）和能源存储（电池）的高性能材料和结构，（b）电动汽车的智能电池的热电学管理，以及（c）器官再生的组织工程技术。由提议的方法提供支持，（i）通过模拟和实验，（ii）优化电池单元和组织生物反应器和实验协议的性能以及（iii），（iii）将支持加拿大的领导力，培训加拿大的全局技术，通过模拟和实验，通过模拟和实验来提高对在纳米，中和宏观尺度上的身体过程的理解，（ii）优化用于多个工程和生物医学学科。该项目的结果将使设计师能够跨多个长度范围量身定制系统的几何形状，材料，结构和操作条件，以彻底改变系统性能。利用这些知识，全球工程师可以释放其潜力和创造力，以设想创新的设计，并通过最先进的计算机模拟快速测试它们，而不是昂贵的，耗时的实验。