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Regulation of Dynamin 2 expression, mitochondrial targeting, and evaluation of its role in mitochondrial fission: Implications for pulmonary arterial hypertension

Regulation of Dynamin 2 expression, mitochondrial targeting, and evaluation of its role in mitochondrial fission: Implications for pulmonary arterial hypertension
Dynamin 2 表达的调节、线粒体靶向及其在线粒体裂变中的作用评估：对肺动脉高压的影响
批准号：
489491
负责人：
Archer Stephen L
金额：
$72.56万
依托单位：
Queen's University (Kingston, Ontario)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2023
资助国家：
加拿大
项目状态：
未结题
起止时间：
2023-09-01 至 2028-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=489491&lang=en
关键词：
Apoptosis Cell Cycle Cell Proliferation Dynamin 2 Epigenetics Mirna Mitochondria Mitochondrial Fission Pulmonary Arterial Hypertension Therapeutics

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Mitochondria are energy producing structures that serve as the "powerhouse of the cell". However, mitochondria also have important non-energetic functions. Mitochondria regulate the rate of cell division (through effects on the cell cycle) and eliminate a
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