)：能够使用现代化学的方法实现分子的组装和剪裁已经成为了化学界所面对的重要基础科学问题。我们以先前对于碳氢活化环合方法学的研究为起点，试图发展一系列的使用相对廉价易得的金属钯催化剂进行的碳氢活化硼基化反应。研究碳氢活化以及有机硼化学的基本科学理论；研究硼化物上不同取代基对产品稳定性及反应活性的影响，尤其聚焦在1. 带有弱导向基团的芳烃的硼化物的制备方法研究；2.非导向的芳烃碳氢活化硼化方法研究；3.烯烃硼化物的碳氢活化合成研究这三个研究方向。发展相应的化学反应新方法，合成一系列具有广泛代表性的芳基以及烯基硼化物。为今后的有机硼化学的进一步研究奠定基础。

A long-standing fundamental scientific challenge in synthetic chemistry is the direct, selective functionalization and construction of molecules under modern tailoring techniques. Based on our preliminary research projects within the development of new C-H activation methodology, in this proposal, we are keen to develop useful synthetic strategies for the synthesis of aryl boran as well as alkenyl boran by utilizing relatively cheap and readily available Pd catalyst. During the research, we are focusing on solving the fundamental science within C-H activation as well as boron chemistry, specifically concentrating on 1. the arenes with weak directing groups, 2. unactivated/directed arenes and 3. alkenes, to develop reliable synthetic approaches and prepare a series of representive aryl and alkenyl borans.