马铃薯是世界第四大粮食作物，块茎既是经济器官和繁殖器官，也是植物变态器官发育研究的模式载体，其形成机制一直是本领域的重点问题。诸多研究表明结薯素SP6A在块茎形成中起着重要调控作用，SP6A通过与其他蛋白形成TAC复合体，从而改变匍匐茎中基因表达实现匍匐茎形态的转变，但TAC复合体调控块茎发育的分子机制仍不清楚。基于此，在SP6A互作蛋白分离和FT-FD类TAC复合体重要组分FDs功能初步鉴定的基础上，本项目拟通过基因时空表达、蛋白互作模式、转录活性调节和下游基因调控网络等方面，系统研究不同类型TAC复合体对块茎形成的调控功能和作用机理，阐释各TAC复合体之间的相互协同或拮抗调控机制，解析TAC复合体下游调控途径及信号传递网络。研究结果将揭示SP6A信号在匍匐茎顶端的传递和调控匍匐茎顶端发育转变的作用模式，丰富和完善光周期诱导的马铃薯块茎形成机理，为光周期适应性改良提供新的基因资源。

Potato is the fourth largest food crop in the world. Tuber is not only an economic organ and a reproductive organ, but also a model species for the study of plant metamorphic organ development. Its formation mechanism has always been a key issue in potato biology. Many studies have shown that the tuberization is regulated by the tuberigen SP6A. SP6A forms the tuberigen activation complex (TAC) with other proteins, thereby altering gene expression in stolons to achieve stolon morphological change. However, the molecular mechanism of tuberization regulated by TAC is still unclear. Based on the separation of SP6A interacting proteins and the preliminary identification of FDs function as an important component of FT-FD TAC, in this project, we intends to analyze the gene space-time expression, protein interaction patterns, transcriptional activity regulation and downstream gene regulation network to systematically study the regulation mechanisms of different TAC on tuberization, uncover the mechanisms of synergistic or antagonistic regulation among TAC, and excavate the downstream regulatory pathways and signal transduction network of TAC. The results will reveal the role of SP6A signal in the transmission and regulation of stolon apical development and transformation, improve the photoperiod-induced tuberization mechanism, and provide new genetic resources for photoperiod adaptation improvement.